CRAB Criteria
- IMWG. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a Report of the International Myeloma Working Group. British Journal of Haematology, 2003; 121: 749-757
- Dimopoulos M, et al. Consensus recommendations for standard investigative workup: report of the International Myeloma Workshop Consensus Panel 3. Blood 2011; 117(18): 4701-470 Calcium elevation: Serum calcium > 11.5 mg/dl [>2.65 mmol/l] Renal failure: Creatinine > 2 mg/dl [177 μmol/l or more] or eGFR < 50 ml/min or eGFR drop over 1 year or cast nephropathy in renal biopsy Anaemia: Haemoglobin < 10 g/dl or 2 g/dl < normal lower limit) [haemoglobin < 12.5 mmol/l or 1.25 mmol/l <normal] or < 2 g/l below normal lower limit, attributable to plasma cell disorder Bone desease: Lytic bone lesions, osteopenia or pathological fracture
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