With both American and international units

Thanks!!

Further comment. As a consultant paediatrician and adolescent physician dealing with many pre-diabetic or at risk of diabetes children, adolescents and adults and needing to priorities who gets scarce resources and which patients need and deserve the extra support and effort to change things, I find HOMA Is a VERY USEFUL tool! It is also useful in motivation of change when I can show meaningful abnormalities in patients who have normal glucose tolerance but are well onto the way to developing T2DM and are at a stage where this can be avoided.

From my reading and what I use, the standard cut-off for upper limit of normal is < 1.6. However, that is only accurate for per pubertal and post pubertal subjects. During puberty insulin sensitivity is decreased as normal process. The best study I have seen that aimed to establish an upper limit of normal during puberty is normal to be < 3.16. So I use <1.6 for pre-pubertal children and in post pubertal adults and < 1.6 for those who have started puberty but not finished puberty or finished growing.

The next question I think is what should be in a HOMA. Whilst insulin is usual, it can be done with c-peptide also and this has advantage of fluctuating less with longer half life and also allows some measurement in those who have been given exogenous insulin.
The HOMA2 calculator at www.dtu.ox.ac.uk/homa has excel file with the calculations though they have a too low upper limit of c-peptide level at least for my patients
3 rd point is units. Any calculator needs to be able to use the reported units and these vary even within countries. insulin can be in mIU/L or in pmol/L. In my institution C-peptide is in nmol/L but may have other units and of course glucose can be mmol/L or mg/dl. Etc.

HOMA-IR = ( Insulina uU /ml X Glucosa mg / dl ) / 22.5
Sensibilidad (S) >= 3.2 ¡Positivos!.
Especificad (E) < 3.2 (óptimo 2.6) = Negativos.
Otros Parámetros:
< 3 Resistencia Normal a la Insulina.
( 3.2 + 2.6 = 5.8 /2 = 2.9 < 3)
Entre 3 y 5 Moderada RI
> 5 RI Grave.

We have started this formula, so a question to you all:

What cut-off would you like us to set for normal / insulin resistance? It would be nicer to have some interpretation to offer our users, but it seems the cut-off is different in many publications/demographics.

As a consultant diabetologist, I would not use this so give us a useful formula instead, like the thyroid storm one.

Fundamental para a pratica clinica atual.

Need more and more as obesity rates going up

Imprescindible

Es necesario que incluyan el cálculo del Homma. Buen indicador de resistencia a la insulina, permite h acer medicina preventiva.

Need it!!!

Need it

Ｉuse everyday

Homa é muito útil na prática clinica, deveria ser acrescentado ao medcalc

Homa-IR is fundamental in Clinical medicine!

Es necesario el uso del HOMA para determinar la resistencia a insulina

This is a must

(Spanish)
Me sorprendió no encontrar el indice HOMA entre las formulas de medcalc. El calculo es sencillo y con frecuencia se requiere.