Abnormal hemoglobin (Hb) levels can affect the diffusing capacity and, if known, should be used to mathematically correct the measured diffusing capacity to normal Hb.

Adjusted DLCO (adolescent males and men): Hb adjusted DLCO (DLCOc) = measured DLCO ([10.22 + Hb g/dL]/[1.7 Hb])

Hb adjusted DLCO (children < 15 y and women): Hb adjusted DLCO (DLCOc) = measured DLCO ([9.38 + Hb g/dL]/[1.7 Hb])

The measured DLCO also can be adjusted for elevated levels of carboxyhemoglobin, as follows: Carboxyhemoglobin-adjusted DLCO (DLCOc) = measured DLCO (1 + [%CO Hb/100])
Or see:
-http://transplant.mednet.ucla.edu/forms/bmt_dlcp.htm.
-http://www.dynamicmt.com/DLCOadjust.html.